Systematic analysis of freshwater metal toxicity with WHAM-FTOX

Tipping, E. ORCID: https://orcid.org/0000-0001-6618-6512; Stockdale, A.; Lofts, S. ORCID: https://orcid.org/0000-0002-3627-851X. 2019 Systematic analysis of freshwater metal toxicity with WHAM-FTOX. Aquatic Toxicology, 212. 128-137. 10.1016/j.aquatox.2019.04.022

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Official URL: https://doi.org/10.1016/j.aquatox.2019.04.022

Abstract/Summary

We used the WHAM chemical speciation model and the WHAM-FTOX toxicity model to analyse the published results of laboratory toxicity experiments covering 52 different freshwater biological test species and 24 different metals, a total of 2037 determinations of EC50 with accompanying data on solution composition. The key extracted parameter was αM, the parameter in WHAM-FTOX that characterises the toxic potency of a metal on the basis of its estimated metabolically active body burden. For 16 data sets applying to metal-test species pairs with appreciable variations in solution composition, values of EC50 back-calculated from averaged values of αM showed significantly (p < 0.001) less deviation from the measured EC50 values than did the simple average EC50, confirming that the modelling calculations could account for some of the dependence of toxicity on chemical speciation. Data for different exposure times permitted a simple parameterisation of temporal effects, enabling values of αM,max (values at infinite exposure time) to be obtained, and the effects of different exposure times to be factored out for further analysis. Comparison of averaged values of αM,max for different metals showed little difference among major taxa (invertebrates, plants, and vertebrates). For Cd, Cu, Ni and Zn (the four metals with most data) there were significant differences among αM,max values for different species, but within-species variabilities were greater. Reasonably similar species sensitivity distributions of standardised αM,max applied to Cd, Cu, Ni and Zn. The average values, over all species, of αM,max increased in the order Al < lanthanides < Zn ∼ UO2 < Ni ∼ Cu < Pb < Cd < Ag. Considering all the αM,max values, there was a strong dependence (r2 = 0.56, p < 0.001) on Pearson’s hardness-softness categories, and a slightly stronger relationship (r2 = 0.59) if ionic radius was included in the statistical model, indicating that softer, larger cations are the most effective toxicants.

Item Type:	Publication - Article
Digital Object Identifier (DOI):	10.1016/j.aquatox.2019.04.022
UKCEH and CEH Sections/Science Areas:	Pollution (Science Area 2017-) UKCEH Fellows
ISSN:	0166-445X
Additional Keywords:	chemical speciation, meta-analysis, metals, toxicity, WHAM, WHAM-FTOX
NORA Subject Terms:	Ecology and Environment
Date made live:	31 May 2019 09:50 +0 (UTC)
URI:	https://nora.nerc.ac.uk/id/eprint/523375

Item Type:

Publication - Article

Digital Object Identifier (DOI):

10.1016/j.aquatox.2019.04.022

UKCEH and CEH Sections/Science Areas:

Pollution (Science Area 2017-)
UKCEH Fellows

ISSN:

0166-445X

Additional Keywords:

chemical speciation, meta-analysis, metals, toxicity, WHAM, WHAM-FTOX

NORA Subject Terms:

Ecology and Environment