Dixit, Kunal 
ORCID: https://orcid.org/0000-0002-1334-6997; Busi, Susheel Bhanu ORCID: https://orcid.org/0000-0001-7559-3400; Ahmed, Anam; Kshirsagar, Avinash; Jäger, Christian; Singh, Alka; Shah, Varun; Saroj, Sunil D.; Ahuja, Vineet; Wilmes, Paul; Shouche, Yogesh; Makharia, Govind ORCID: https://orcid.org/0000-0002-2474-2194; Dhotre, Dhiraj ORCID: https://orcid.org/0000-0002-5000-7396.
2026
Multi-meta-omics reveal distinct microbial genomic profiles and metabolic dysregulation in non-celiac gluten sensitivity.
mSphere, 0:e00856-25.
15, pp.
10.1128/msphere.00856-25
Non-celiac gluten sensitivity (NCGS) is an emerging diagnosis with symptoms that overlap with irritable bowel syndrome (IBS). Using shotgun metagenomics and metabolomics, we report deeper insights into the microbiome profile, including viral and archaeal diversity, lower fructan degradation potential, the differential abundance of metabolites, and genomic features of gut bacteria in patients with NCGS. Understanding the microbiome associated with this disorder may shed light on the possible role of the microbiome in the pathophysiology of NCGS.
Available under License Creative Commons Attribution 4.0.
Download (2MB) | Preview
Downloads per month over past year
Altmetric Badge
Dimensions Badge
 |