Huang, Wei E.; Ude, Susanne; Spiers, Andrew J.. 2007 Pseudomonas fluorescens SBW25 biofilm and planktonic cells have differentiable Raman Spectral Profiles. Microbial Ecology, 53 (3). 471-474. 10.1007/s00248-006-9190-1
Abstract
Biofilms, and other bacterial aggregations, are of significance in both environmental microbiology and in plant and human pathogenesis. Comparative single-cell Raman spectral analysis can differentiate between planktonic bacteria and those recovered from biofilms and appears to offer a new means by which to investigate bacterial cell physiology, metabolic status, and stress under different environmental conditions.
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