Benign circulation of rabbit haemorrhagic disease virus on Lambay Island, Eire

Forrester, N.L; Trout, R.C.; Gould, E.A.. 2007 Benign circulation of rabbit haemorrhagic disease virus on Lambay Island, Eire. Virology, 358 (1). 18-22. 10.1016/j.virol.2006.09.011

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Abstract/Summary

With the exception of virus strains Ashington and RCV, other recognised strains of Rabbit haemorrhagic disease virus (RHDV) share relatively close genetic homology. Using serology and phylogenetic analysis, we have identified a third disparate virus lineage in healthy rabbits on Lambay Island off the east coast of Eire, where disease due to RHDV has never been observed. ELISA tests revealed high titre RHDV-specific antibodies in 81% of the sera from 11 healthy rabbits captured on this island, indicating that the virus is actively circulating amongst these rabbits. Nevertheless, infectious virus has not been isolated from rabbits living on this island. The detection of antibodies and the disparate Lambay virus lineage in an apparently healthy and isolated wild rabbit population provides the most convincing evidence yet that at least some strains of RHDV can circulate harmlessly for long periods of time in wild rabbits possibly by producing persistent or latent infections.

Item Type:	Publication - Article
Digital Object Identifier (DOI):	10.1016/j.virol.2006.09.011
Programmes:	CEH Programmes pre-2009 publications > Biodiversity
UKCEH and CEH Sections/Science Areas:	Hails
ISSN:	0042-6822
Additional Keywords:	Rabbit haemorrhagic disease virus
NORA Subject Terms:	Biology and Microbiology
Date made live:	13 Dec 2007 14:47 +0 (UTC)
URI:	https://nora.nerc.ac.uk/id/eprint/1593

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