Genomic regions in crop-wild hybrids of lettuce are affected differently in different environments: implications for crop breeding

Hartman, Yorike; Hooftman, Danny A.P.; Uwimana, Brigitte; van de Wiel, Clemens C.M.; Smulders, Marinus J.M.; Visser, Richard G.F.; van Tienderen, Peter H.. 2012 Genomic regions in crop-wild hybrids of lettuce are affected differently in different environments: implications for crop breeding. Evolutionary Applications, 5 (6). 629-640.

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Many crops contain domestication genes that are generally considered to lower fitness of crop–wild hybrids in the wild environment. Transgenes placed in close linkage with such genes would be less likely to spread into a wild population. Therefore, for environmental risk assessment of GM crops, it is important to know whether genomic regions with such genes exist, and how they affect fitness. We performed quantitative trait loci (QTL) analyses on fitness(-related) traits in two different field environments employing recombinant inbred lines from a cross between cultivated Lactuca sativa and its wild relative Lactuca serriola. We identified a region on linkage group 5 where the crop allele consistently conferred a selective advantage (increasing fitness to 212% and 214%), whereas on linkage group 7, a region conferred a selective disadvantage (reducing fitness to 26% and 5%), mainly through delaying flowering. The probability for a putative transgene spreading would therefore depend strongly on the insertion location. Comparison of these field results with greenhouse data from a previous study using the same lines showed considerable differences in QTL patterns. This indicates that care should be taken when extrapolating experiments from the greenhouse, and that the impact of domestication genes has to be assessed under field conditions.

Item Type: Publication - Article
Digital Object Identifier (DOI):
Programmes: CEH Topics & Objectives 2009 - 2012 > Biodiversity > BD Topic 2 - Ecological Processes in the Environment > BD - 2.3 - Identify indicators and traits of ecosystem status ...
CEH Topics & Objectives 2009 - 2012 > Biodiversity > BD Topic 1 - Observations, Patterns, and Predictions for Biodiversity > BD - 1.3 - Long-term/large-scale monitoring and experiments ...
UKCEH and CEH Sections/Science Areas: Hails
ISSN: 1752-4563
Additional Information. Not used in RCUK Gateway to Research.: This is an open access article - to access full text, please click on the Official URL link
Additional Keywords: crop–wild hybrids, fitness, hitchhiking, Lactuca, mitigation strategy, quantitative trait loci, selection, transgenic plants
NORA Subject Terms: Biology and Microbiology
Date made live: 09 Mar 2012 11:41 +0 (UTC)

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