Modelling Aedes aegypti mosquito control via transgenic and sterile insect techniques: endemics and emerging outbreaks

Seirin Lee, S.; Baker, R.E.; Gaffney, E.A.; White, S.M. ORCID: https://orcid.org/0000-0002-3192-9969. 2013 Modelling Aedes aegypti mosquito control via transgenic and sterile insect techniques: endemics and emerging outbreaks. Journal of Theoretical Biology, 331. 78-90. 10.1016/j.jtbi.2013.04.014

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Official URL: http://dx.doi.org/10.1016/j.jtbi.2013.04.014

Abstract/Summary

The invasion of pest insects often changes or destroys a native ecosystem,and can result in food shortages and disease endemics.Issues such as the environmental effects of chemical control methods,the economic burden of maintaining control strategies and the risk of pestresistance still remain,and mosquito-borne diseases such as malaria and dengue fever prevail in many countries,infecting over100 million worldwide in 2010.One environmentally friendly method for mosquito control is the Sterile Insect Technique(SIT).This species-specific method of insect control relies on the mass rearing, sterilization and release of large numbers of sterile insects.An alternative transgenic method is the Release of Insects carrying a Dominant Lethal(RIDL).Our objective is to consider contrasting control strategies for two invasive scenarios via SIT and RIDL:an endemic case and an emerging outbreak. We investigate how the release rate and size of release region influence both the potential for control success and there sources needed to achieve it,under a range of conditions and control strategies,and we discuss advantageous strategies with respect to reducing the release resources and strategy costs(in terms of control mosquito numbers)required to achieve complete eradication of wild-type mosquitoes.

Item Type:	Publication - Article
Digital Object Identifier (DOI):	10.1016/j.jtbi.2013.04.014
Programmes:	CEH Topics & Objectives 2009 - 2012 > Biodiversity > BD Topic 3 - Managing Biodiversity and Ecosystem Services in a Changing Environment CEH Topics & Objectives 2009 - 2012 > Biodiversity > BD Topic 1 - Observations, Patterns, and Predictions for Biodiversity
UKCEH and CEH Sections/Science Areas:	Pywell
ISSN:	0022-5193
Additional Keywords:	biological control, Aedes aegypti, RIDL, SIT, transgenic insects
NORA Subject Terms:	Biology and Microbiology
Date made live:	09 Jul 2013 14:50 +0 (UTC)
URI:	https://nora.nerc.ac.uk/id/eprint/502553

Item Type:

Publication - Article

Digital Object Identifier (DOI):

10.1016/j.jtbi.2013.04.014

Programmes:

CEH Topics & Objectives 2009 - 2012 > Biodiversity > BD Topic 3 - Managing Biodiversity and Ecosystem Services in a Changing Environment
CEH Topics & Objectives 2009 - 2012 > Biodiversity > BD Topic 1 - Observations, Patterns, and Predictions for Biodiversity

UKCEH and CEH Sections/Science Areas:

Pywell

ISSN:

0022-5193

Additional Keywords:

biological control, Aedes aegypti, RIDL, SIT, transgenic insects