nerc.ac.uk

Acylated homoserine lactones in the environment: chameleons of bioactivity

Manefield, Mike; Whiteley, Andrew S.. 2007 Acylated homoserine lactones in the environment: chameleons of bioactivity. Phil. Trans Royal Soc. B., 362 (1483). 1235-1240. https://doi.org/10.1098/rstb.2007.2048

Full text not available from this repository.

Abstract/Summary

Over the last 15 years, it has become increasingly apparent that a single class of compounds, the acylated homoserine lactones (AHLs), elicit effects on many levels of biological and ecological organization. Despite the fact that the distribution of AHL production in the prokaryotic phylogenetic tree is restricted to a small set of genera, representatives of these genera are abundant in the environment and are responsible for processes of much interest to humans. As well as driving interactions between clones, AHLs have been shown to mediate interactions between different species of bacteria and between bacteria and higher organisms, either through the phenotypes they regulate or directly through their own chemical behaviour. Understanding the biological activity of AHLs and the ecological consequences of these activities may provide us with an opportunity to manipulate the composition and function of complex biological assemblages. Ultimately, this broadens the biotechnological focus of AHL-based research beyond the attenuation of virulence in humans and plant pathogens.

Item Type: Publication - Article
Digital Object Identifier (DOI): https://doi.org/10.1098/rstb.2007.2048
Programmes: CEH Programmes pre-2009 publications > Biodiversity > BD03 The Genetic Basis of Ecological Function > BD03.1 Molecular ecology
UKCEH and CEH Sections/Science Areas: Hails
Additional Keywords: acylated homoserine lactone, microbial ecology, microbial communities
NORA Subject Terms: Biology and Microbiology
Date made live: 01 Dec 2008 16:18 +0 (UTC)
URI: https://nora.nerc.ac.uk/id/eprint/4871

Actions (login required)

View Item View Item

Document Downloads

Downloads for past 30 days

Downloads per month over past year

More statistics for this item...