Towards a model for the dynamic transfer of tritium and carbon in mammals

Galeriu, D.; Beresford, N.A.; Takeda, H.; Melintescu, A.; Crout, N.M.J.. 2003 Towards a model for the dynamic transfer of tritium and carbon in mammals. Radiation Protection Dosimetry, 105 (1-4). 387-390.

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Abstract/Summary

Available data have been analysed to test the hypothesis that both 3H and 14C transfer in mammals can be accounted for by an understanding of metabolism. Data obtained from various 14C and 3H experiments with rats and sheep have been analysed to assess the multi-component retention function of various organs and identify any relationship between half-times and component contribution. Our hypothesis was that component half-times for 14C and 3H are similar after intakes of organic compounds. Similarities in the tritium and carbon dynamics between rat and sheep were observed supporting the hypothesis. For fast and slow components of muscle half-time, allometric relationships have been derived. The results obtained could be used in the development of a human biokinetic model.

Item Type:	Publication - Article
Programmes:	CEH Programmes pre-2009 publications > Biogeochemistry > SE01B Sustainable Monitoring, Risk Assessment and Management of Chemicals > SE01.4 Monitoring and predicting the distribution of chemicals in terrestrial and freshwater ecosystems
UKCEH and CEH Sections/Science Areas:	_ Environmental Chemistry & Pollution
ISSN:	0144-8420
Additional Keywords:	radioecology
NORA Subject Terms:	Ecology and Environment
Date made live:	26 Apr 2012 11:15 +0 (UTC)
URI:	https://nora.nerc.ac.uk/id/eprint/17738

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