Tick cell lines: tools for tick and tick-borne disease research
Bell-Sakyi, Lesley; Zweygarth, Erich; Blouin, Edmour F.; Gould, Ernest A.; Jongejan, Frans. 2007 Tick cell lines: tools for tick and tick-borne disease research. Trends in Parasitology, 23 (9). 450-457. 10.1016/j.pt.2007.07.009Full text not available from this repository.
Over 40 cell lines are currently available from 13 ixodid and one argasid tick species. The successful isolation and propagation of several economically important tick-borne pathogens in tick cell lines has created a useful model to study interactions between tick cells and these viral and bacterial disease agents. Tick cell lines have already proved to be a useful tool in helping to define the complex nature of the host–vector–pathogen relationship. With the availability of genomics tools, tick cell lines will become increasingly important as a complement to tick and tick-borne disease research in vivo once genetic transformation and gene silencing using RNA interference become routine.
|Item Type:||Publication - Article|
|Digital Object Identifier (DOI):||10.1016/j.pt.2007.07.009|
|Programmes:||CEH Programmes pre-2009 publications > Biodiversity|
|NORA Subject Terms:||Biology and Microbiology
|Date made live:||15 Jan 2008 16:41|
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