The effectiveness of oral administration of potassium iodide to lactating goats in reducing the transfer of radioiodine to milk
Beresford, N.A.; Mayes, R.W.; Barnett, C.L.; Lamb, C.S.; Wilson, P.J.; Howard, B.J.; Voigt, G.. 1997 The effectiveness of oral administration of potassium iodide to lactating goats in reducing the transfer of radioiodine to milk. Journal of Environmental Radioactivity, 35 (2). 115-128. 10.1016/S0265-931X(96)00050-1Full text not available from this repository.
Ingestion of milk contaminated by radioiodine (most especially 131I) represents an important potential route of radiation exposure to humans in the event of a nuclear accident. Oraladministration of stable iodine to dairy ruminants has previously been suggested as an effective countermeasure to reduce radioiodine levels in milk. However, previous data on its effectiveness are contradictory, and little attention has been given to the most appropriate time to administer stable iodine relative to the time that an animal is first exposed to radioiodine. The effectiveness of 1g KI orally administered to lactating goats 12 h before and 12 h after contamination with pulse doses of radioiodine was investigated. Administration of KI prior to the ingestion of radioiodine was shown to reduce the transfer to milk by 50% compared to a reduction of approximately 40% when KI was administered 12 h after radioiodine. The administration of KI 12 h prior to radioiodine contamination effectively reduced the transfer of radioiodine to the thyroid by approximately 90%. When administered 12 h after radioiodine, the KI stopped subsequent uptake of radioiodine by the thyroid. The maximum level of iodine in milk, as a consequence of the administration of KI, was 20 mg I kg−1. This was 40-fold higher than the maximum permissible level of iodine in milk of 0.5 mg l−1 currently set in some countries. Further consideration is required on stable iodine administration regimes for different scenarios and the consequent increase in the stable iodine content of the milk of different dairy animals
|Programmes:||CEH Programmes pre-2009 publications > Other|
|CEH Sections:||_ Pre-2000 sections|
|NORA Subject Terms:||Ecology and Environment|
|Date made live:||06 Jun 2012 11:02|
Actions (login required)