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The virology, epidemiology, and clinical impact of West Nile virus: a decade of advancements in research since its introduction into the Western Hemisphere

Murray, K.O.; Walker, C.; Gould, E.. 2011 The virology, epidemiology, and clinical impact of West Nile virus: a decade of advancements in research since its introduction into the Western Hemisphere. Epidemiology and Infection, 139 (6). 807-817. 10.1017/S0950268811000185

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Abstract/Summary

West Nile virus (WNV) is now endemic in the USA. After the widespread surge of virus activity across the USA, research has flourished, and our knowledge base has significantly expanded over the past 10 years since WNV was first recognized in New York City. This article provides a review of the virology of WNV, history, epidemiology, clinical features, pathology of infection, the innate and adaptive immune response, host risk factors for developing severe disease, clinical sequelae following severe disease, chronic infection, and the future of prevention.

Item Type: Publication - Article
Digital Object Identifier (DOI): 10.1017/S0950268811000185
Programmes: CEH Topics & Objectives 2009 - 2012 > Biodiversity > BD Topic 2 - Ecological Processes in the Environment > BD - 2.2 - Quantify the impact of invasive species, pathogens ...
CEH Sections: CEH fellows
ISSN: 0950-2688
Additional Keywords: clinical features, epidemiology, outcomes, vaccination, West Nile virus
NORA Subject Terms: Biology and Microbiology
Ecology and Environment
Date made live: 07 Sep 2011 13:44
URI: http://nora.nerc.ac.uk/id/eprint/15059

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