West Nile Virus: Don't Underestimate Its Persistence

Gould, Earnest A.. 2010 West Nile Virus: Don't Underestimate Its Persistence. Journal of Infectious Diseases, 20 (1). 1. 10.1086/648732

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An interesting report in this issue of the Journal by Murray et al [ 1] provides compelling evidence that West Nile virus (WNV) can persist for years in the kidneys of humans convalescing from infection with this virus. Furthermore, WNV, as detected in the form of genomic RNA, was excreted in the urine for 6 years or more after recovery from acute disease. As discussed below, these findings could have important implications for flavivirus epidemiology and pathogenesis One of the many questions that occupy the minds of virologists is, what do pathogenic viruses do when they are not causing overt disease transmission?. We are all familiar with the concept of acute viremic …

Item Type: Publication - Article
Digital Object Identifier (DOI): 10.1086/648732
Programmes: CEH Topics & Objectives 2009 - 2012 > Biodiversity
CEH Sections: CEH fellows
ISSN: 0022-1899
NORA Subject Terms: Biology and Microbiology
Date made live: 02 Mar 2011 13:54

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